TABLE 4

Myocellular fatty acyl CoA concentrations

PalmitoleoylLinoleoyl and arachidonylPalmitoylOleoylStearoylTotal
Pre-acipimox
    Basal0.19 ± 0.103.50 ± 1.331.89 ± 0.573.28 ± 1.181.49 ± 0.3410.3 ± 1.9
    Insulin0.007 ± 0.005*2.16 ± 0.650.57 ± 0.11*0.69 ± 0.26 *0.64 ± 0.154.06 ± 0.78
Post-acipimox
    Basal0.05 ± 0.051.50 ± 0.590.61 ± 0.191.33 ± 0.311.05 ± 0.314.54 ± 0.82§
    Insulin0.07 ± 0.071.08 ± 0.450.44 ± 0.170.53 ± 0.170.63 ± 0.152.76 ± 0.57*
  • Data are means ± SE in units of picomoles per milligram of muscle wet weight.

  • *

    * P < 0.05,

  • P < 0.01 vs. basal,

  • P < 0.05 vs. pre-acipimox,

  • §

    § P < 0.01 vs. pre-acipimox.