TABLE 1

ARC glucosensing neurons (6,9)

Glucosensing neuronsGlucose responses
Mechanism involved
Glucose sensitivity range <5 mmol/lGlucose sensitivity range >5 mmol/l
Glucose change testedDecrease (2.5 → 0.1 mmol/l)Increase (5 → 20 mmol/l)
GEInhibition?KATP
GIExcitation??
HGE?ExcitationNonselective cationic conductance
HGI?Inhibition?
  • GE, glucose excited; GI, glucose inhibited; HGE, high glucose excited; HGI, high glucose inhibited. ?, unknown.