TABLE 2

Genotype distributions of polymorphism in ADIPOR1 and ADIPOR2 genes in diabetic case and control subjects

PolymorphismsCase (%)/control (%) by genotype
Odds ratio (95% CI)
Homozygote, majorHeterozygoteHomozygote, minorCrudeAdjusted*
ADIPOR1
    rs2232853341 (49.1)/565 (51.4)297 (42.7)/440 (40.0)57 (8.2)/94 (8.6)1.10 (0.91–1.33)1.16 (0.94–1.43)
    rs10494839340 (48.7)/557 (51.1)296 (42.4)/438 (40.2)62 (8.9)/95 (8.7)1.11 (0.91–1.34)1.17 (0.95–1.44)
    rs12733285344 (49.4)/511 (47.1)293 (42.0)/485 (44.7)60 (8.6)/88 (8.2)0.91 (0.75–1.10)0.87 (0.70–1.07)
    rs1342387210 (30.4)/297 (27.8)347 (50.4)/558 (52.3)132 (19.2)/212 (19.9)0.88 (0.71–1.09)0.77 (0.61–0.98)
    rs1139646290 (43.2)/513 (48.7)306 (45.5)/433 (41.1)76 (11.3)/108 (10.2)1.26 (1.03–1.53)1.36 (1.10–1.70)
    rs10920531266 (37.9)/464 (42.6)329 (46.9)/470 (43.1)107 (15.2)/156 (14.3)1.21 (1.00–1.47)1.33 (1.08–1.65)
ADIPOR2
    rs11061925336 (48.4)/552 (50.7)301 (43.3)/429 (39.4)58 (8.3)/108 (9.9)1.10 (0.90–1.32)1.22 (0.99–1.51)
    rs7132033363 (51.5)/587 (53.2)292 (41.4)/419 (37.9)50 (7.1)/98 (8.9)1.07 (0.88–1.29)1.18 (0.96–1.46)
    rs7975600521 (75.7)/814 (75.7)156 (22.7)/236 (22.0)11 (1.6)/25 (2.3)1.00 (0.80–1.25)1.02 (0.80–1.31)
    rs11061937334 (48.0)/518 (48.1)296 (42.5)/444 (41.3)66 (9.5)/114 (10.6)1.01 (0.83–1.22)1.12 (0.90–1.38)
    rs12826079617 (87.6)/959 (86.7)85 (12.1)/143 (12.9)2 (0.3)/4 (0.4)0.92 (0.69–1.22)1.01 (0.74–1.38)
    rs11061946594 (84.4)/941 (85.0)104 (14.8)/160 (14.5)6 (0.8)/6 (0.5)1.05 (0.81–1.36)1.08 (0.81–1.44)
    rs10773983306 (44.5)/492 (45.5)317 (46.1)/464 (42.9)65 (9.4)/125 (11.6)1.04 (0.86–1.26)1.05 (0.85–1.30)
    rs11612383335 (47.6)/496 (45.9)297 (42.2)/475 (44.0)72 (10.2)/109 (10)0.93 (0.77–1.13)0.98 (0.80–1.21)
    rs1058322323 (46.6)/514 (48.0)300 (43.3)/448 (41.8)70 (10.1)/109 (10.2)1.06 (0.87–1.28)1.12 (0.91–1.38)
    rs12230440476 (70.7)/745 (70.8)184 (27.4)/288 (27.4)13 (1.9)/19 (1.8)1.00 (0.81–1.24)1.10 (0.87–1.39)
    rs929434321 (47.2)/496 (47.6)295 (43.3)/435 (41.8)65 (9.5)/110 (10.6)1.02 (0.84–1.24)1.13 (0.91–1.40)
    rs11061971216 (31.4)/335 (31.2)337 (49.0)/510 (47.6)135 (19.6)/227 (21.2)0.99 (0.80–1.22)1.09 (0.86–1.37)
    rs11061973501 (72.7)/783 (72.1)173 (25.1)/284 (26.1)15 (2.2)/19 (1.8)0.97 (0.78–1.20)1.02 (0.80–1.28)
    rs2108642195 (28.1)/313 (28.8)343 (49.4)/516 (47.4)156 (22.5)/259 (23.8)1.03 (0.84–1.28)1.16 (0.92–1.46)
    rs7316374542 (76.6)/818 (74.1)156 (22.0)/267 (24.2)10 (1.4)/19 (1.7)0.88 (0.70–1.09)0.89 (0.70–1.13)
    rs1044471185 (27.3)/319 (29.6)329 (48.4)/514 (47.8)165 (24.3)/243 (22.6)1.12 (0.91–1.39)1.11 (0.87–1.40)
  • rs1139646 is also known as rs7539542.

  • *

    * Adjusted for age, BMI, alcohol consumption, smoking, physical activity, family history of diabetes, and menopausal status—under dominant inheritance mode.