TABLE 2

Subject characteristics

GDM probandsSiblingsCousinsControl subjects
n9424117958
Male/female0/9488/15380/990/58
Age (years)35.0 (8.6)34.5 (11.0)32.8 (11.8)33.4 (7.6)
BMI (kg/m2)30.9 (8.9)29.1 (6.3)27.4 (6.6)27.2 (6.6)
Body fat (%)39.1 (7.3)33.5 (13.9)30.7 (12.8)36.0 (7.0)
Fasting glucose (mmol/l)5.4 (0.9)5.1 (0.6)5.1 (0.6)4.9 (0.4)
2-h glucose (mmol/l)8.4 (3.4)7.3 (2.6)6.4 (2.2)6.9 (2.1)
Fasting insulin (pmol/l)69 (48)42 (42)36 (36)30 (36)
2-h insulin (pmol/l)522 (462)372 (378)300 (336)252 (312)
30’ Δinsulin (pmol/l)372 (252)321 (252)366 (342)294 (324)
SG (×10−2 per min−1)1.29 (0.41)1.55 (0.71)1.74 (0.88)1.84 (0.94)
SI (×10−3 per min−1 per pmol/l)3.63 (2.06)4.32 (3.28)4.85 (3.17)5.67 (3.01)
AIR (pmol/l × 10 min)1,990 (2,648)2,572 (2,788)3,044 (3,610)2,974 (2,348)
DI780 (780)1,141 (1,145)1,339 (1,106)1,714 (972)
  • Data are unadjusted median (interquartile range) unless otherwise indicated.