TABLE 1

Plasma metabolic parameters of mice used in this study

C57BL/6JapoE−/−ob/obob/ob;apoE−/−
n5554
TC (mg/dl)121.0 ± 31.6442 ± 65.0*217 ± 66.6728.3 ± 156.1
TG (mg/dl)51.3 ± 15.689.3 ± 14.7107.0 ± 23.1180.3 ± 36.0§
FFA (mmol/l)0.49 ± 0.160.50 ± 0.110.78 ± 0.150.86 ± 0.23
Glucose (mg/dl)125 ± 2.1113 ± 6.7118 ± 12132 ± 25
Insulin (ng/ml)0.89 ± 0.190.86 ± 0.2217 ± 3.431 ± 8.5
  • Data are means ± SD. Six-month-old mice were kept on a standard chow diet. Plasma total cholesterol (TC), triglyceride (TG), and FFA levels were measured using enzymatic methods. Statistical analysis was performed using the Student's t test:

  • *

    * P < 0.01 vs. C57BL/6J,

  • P < 0.01 vs. ob/ob,

  • P < 0.05 vs. C57BL/6J,

  • §

    § P < 0.05 vs. ob/ob.

  • Values were taken from a previously published study (16).