TABLE 3

Insulitis, β-cell surface area, and β-cell proliferation in aAb+ organ donors

No. of aAbsCase subjectNo. of islets with insulitis/total islets examinedRelative β-cell surface area [% (range)]Ki67+ INS+ cells/INS+ cells ‰ (range)
415/581.9549*/0†
3227/9171.590
30/991.460
240/1161.500
50/1370.820
60/1410.790
70/3311.280
1n = 550/10,2231.13 (0.50–2.80)0.4 (0–5)
0n = 620/10,3341.21 (0.51–2.61)0.4 (0–7)
  • *

    * Ki67+ ins+ cell number in islets with insulitis. †Ki67+ ins+ cell number in islets with no signs of insulitis.