TABLE 2

Gene transcripts downregulated in Ngn3−/− pancreas at E18.5 versus expression levels in adult CD1 mouse islets

Genbank IDFold change E18.5 (wild type/Ngn3−/−)Expression in adult islets
GcgAF2767541,364.054,221.21
IappBM569571965.053,018.00
Ins1NM_008386405.048,271.76
Ins2NM_008387497.740,357.31
IappBB434117805.038,126.00
Scg5AK0193375.534,706.20
PpyNM_0089187.832,143.54
ChgaNM_00769343.225,948.83
Tmem27AI31469466.521,253.26
G6pc2Z4778743.921,243.67
Scg3NM_00913031.720,934.01
SstNM_009215165.119,871.07
ChgbNM_00769497.015,589.74
PyyBC01082164.314,889.29
Pcsk2AI83970023.613,963.12
Pcsk2NM_00879262.912,877.78
Slc30a8 (ZnT8)BB43366718.69,643.99
IappBM56957194.08,830.73
Gja9BI7378429.67,247.54
BB33625629.97,043.94
Insm1BB46841012.66,996.37
Neurod1BM1165927.96,698.26
AW4932914.36,392.52
Abcc8BB5159484.36,098.58
Sytl4NM_0137578.36,038.47
4930544G21RikAV32754920.35,745.73
BB3494725.05,704.96
Papss2BF7860724.13,892.62
4930488E11RikAW9124174.83,417.22
Lrp11BB4353487.13,342.56
BC0182494.03,276.17
AI987662AV2821518.33,202.88
Syt13BB2445856.73,183.86
Sez6l2AW1215115.63,154.09
Isl1BQ1769158.42,971.00
Pcsk1nAF1815604.92,950.96
Pax6BC0112728.82,943.98
BG0657826.42,905.03
Papss2BF7860725.62,790.13
Ppp1r1aNM_0213917.82,740.16
Gch1BB6983984.42,584.94
Neurod1BM11659233.62,444.55
FrzbU919054.42,348.46
ScgnBC0160937.52,159.75
1700086L19RikBI52603312.02,089.92
Rbp4U631464.32,026.31
Isl1BQ1769158.91,928.84
IappBB43411711.01,829.83
AI4297456.51,820.01
CadpsNM_0120617.71,811.08
AV3078608.11,779.41
Syt7AV1384384.71,772.53
Atp2a3NM_0167454.31,754.10
Fkbp1bNM_0168635.71,730.78
MlxiplAF24547926.61,727.16
Zdhhc2BB2246584.11,564.37
Nol4AV3230334.91,427.26
Slc2a5NM_0197416.51,377.04
Abcc8BF4665695.31,337.43
Disp2BB02374319.31,320.44
Nkx6–1AF3578834.91,255.80
NpyNM_0234566.21,220.19
Insm1NM_01688913.21,168.05
Pcsk2BB3579754.31,057.46
Spock2BM1176726.6981.56
Chic1Y118964.4879.21
Zcchc18BC0176275.1841.97
Pcsk2AI8397004.1784.11
BB2624154.5758.46
Camk2bNM_0075955.3749.76
Gtpbp4AI9878345.3681.42
AK0156427.0625.43
BE9485056.1615.68
Fabp1NM_0173994.2562.39
Upb1NM_13399514.9518.36
Rimbp2BQ1744704.6491.47
Pak3BQ1757964.3472.47
BC026682NM_0255906.0415.94
BC052055BB3929845.1336.12
AV0301187.0303.42
BC038479AV3673954.2293.78
Cplx2BE9462384.0292.95
Ankrd40AK0174514.5289.60
Baiap3BC02265925.2288.45
BQ1756364.5263.94
Ush1cNM_0236494.0251.60
BB0841324.9245.63
1100001E04RikBB3675907.1242.20
2410129H14RikBI1531334.5239.18
BM2137784.4209.61
AV3297904.4201.61
PhyhiplAI2670485.3171.28
AI467606BB2343374.3161.34
NnatAV2188415.4152.18
Pak3BQ1749354.5148.61
BC051142AV2783214.7137.10
Akap10AK0053257.6122.61
Stk32aBB2790834.1117.41
C8bBC0221294.1113.72
C775014.9113.19
Smarca2BM2302025.0112.24
Hist3h2aAV2976516.0109.44
H2-K1M581564.2100.31