TABLE 5

Diabetic NF-κB p50−/− mice do not develop tactile allodynia

50% Withdrawal threshold (g)
B6129PF2/J wild-type miceNF-κB p50−/− mice
Normal5.93 ± 0.214.54 ± 1.59
Diabetic0.84 ± 0.46*5.59 ± 0.66
  • Data are means ± SD of 8–9 wild-type and 18–19 knockout mice. Behavioral measurements were performed 6 months after induction of experimental diabetes.

  • *

    * Significantly different from normal mice at P < 0.01 (Kruskal-Wallis test, followed by Dunn's test).