TABLE 2

Unadjusted baseline characteristics in the three groups based on patterns of the persistence of pre-diabetes over 4 years

NeverIntermittentPersistentP value
Age (years)10.9 ± 1.911.0 ± 1.711.9 ± 1.6NS
Sex (% girls)513863NS
Tanner stage2.3 ± 1.31.9 ± 1.22.8 ± 1.70.051
Weight (kg)63.0 ± 19.763.0 ± 19.372.0 ± 21.2NS
BMI percentile96.6 ± 4.297.4 ± 2.897.0 ± 3.7NS
Waist (cm)85.9 ± 13.688.7 ± 13.092.1 ± 13.5NS
Fat mass (kg)24.3 ± 10.324.7 ± 10.329.0 ± 11.7NS
Fat-free mass (kg)36.4 ± 10.035.8 ± 9.940.4 ± 9.2NS
IAAT (cm2)41.5 ± 19.349.6 ± 21.859.4 ± 22.10.015
SAAT (cm2)325.0 ± 159.3319.6 ± 120.1409.4 ± 141.90.1
Fasting glucose (mg/dl)88.5 ± 4.491.6 ± 5.894.3 ± 10.1<0.001
Fasting insulin (μU/ml)18.4 + 12.719.5 + 10.722.6 + 10.9NS
2-h glucose (mg/dl)115.1 ± 11.8130.6 ± 15.1139.6 ± 22.0<0.001
Si (×10−4 min−1 · μU−1 · ml−1)2.4 ± 1.72.1 ± 1.21.6 ± 1.30.1
AIR (μU/ml)1,646 ± 1,2671,752 ± 1,1841,724 ± 1,321NS
Disposition index (×10−4 min−1)2,639 ± 1,0522,746 ± 1,1791,758 ± 1,0500.008
  • Sample size for age, sex, Tanner stage, weight, BMI percentile, fasting glucose and insulin, and 2-h glucose, n = 128 (51 never, 61 intermittent, and 16 persistent). Sample size for waist, fat mass, and lean mass, n = 126 (50 never, 60 intermittent, and 16 persistent), Sample size for Si, AIR, and disposition index, n = 121 (48 never, 57 intermittent, and 16 persistent). Sample size for IAAT and SAT, n = 109 (45 never, 50 intermittent, and 14 persistent).