TABLE 1

Change in body weight and blood glucose

Week
04182629
Body weight (g)
    Control diet
        Wild type26.5 ± 0.730.6 ± 1.034.9 ± 1.837.8 ± 1.737.9 ± 1.4
        α2i TG25.0 ± 0.629.4 ± 0.632.7 ± 1.235.5 ± 1.336.4 ± 1.2
    High-fat diet
        Wild type24.8 ± 0.734.1 ± 0.8*41.3 ± 1.9*47.3 ± 2.5*47.6 ± 2.5*
        α2i TG24.9 ± 0.534.9 ± 0.8*42.7 ± 1.7*49.2 ± 1.0*48.6 ± 1.5*
Blood glucose (mg/dl)
    Control diet
        Wild type190.6 ± 10.8127.8 ± 5.1136.4 ± 6.9130.8 ± 6.9126.6 ± 20.3
        α2i TG165.4 ± 11.4155.0 ± 11.1133.6 ± 12.7122.4 ± 9.3143.5 ± 29.4
    High-fat diet
        Wild type171.8 ± 16.6165.0 ± 12.8149.0 ± 28.6154.5 ± 7.9162.0 ± 17.6*
        α2i TG182.5 ± 12.3160.3 ± 10.8157.2 ± 6.4150.3 ± 14.3191.5 ± 18.3
  • Data are means ± SE. n = 5–6 for all points.

  • *

    * P < 0.01 vs. control diet in same genotype.

  • P < 0.05 vs. control diet in same genotype.