TABLE 1

Metabolic characteristics and systolic blood pressure of ESMIRO mice compared with their wild-type littermates

Wild typeESMIROP value
Fasting blood sugar (mmol/l)6.7 ± 0.46.5 ± 0.20.68
Postglucose blood sugar (mmol/l)16.2 ± 1.014.4 ± 0.70.17
Random blood glucose (mmol/l)11.1 ± 1.113.3 ± 1.10.19
Fasting insulin (ng/ml)0.30 ± 0.030.34 ± 0.030.27
Postglucose insulin (ng/ml)0.72 ± 0.060.78 ± 0.100.61
HOMA-IR2.4 ± 0.62.1 ± 0.20.63
Fasted triglycerides (mmol/l)0.98 ± 0.140.8 ± 0.080.28
Fasted free fatty acids (mmol/l)1.0 ± 0.20.92 ± 0.10.49
Systolic blood pressure (mmHg)131 ± 4129 ± 40.68
  • Data are means ± SE (n = 8). No significant differences were noted between the two groups.