TABLE 1

Characteristics at entry and at exam 7 of 2,543 FOS participants genotyped for ADIPOQ variants

nMean ± SD
Total individuals genotyped (n)2,543
Unrelated (n)1,448
Pedigrees (n)282
Sibpairs (n)994
Avuncular pairs (n)66
Cousins (n)653
Sex (% women)2,54353
Age at entry (exam 1) (years)2,54334.6 ± 9.8
BMI at entry (exam 1) (kg/m2)254324.9 ± 4.3
Cases of diabetes over 28 years (n)244
Mean glucose from exams 1–7 (mg/dl)2,54399.3 ± 16.9
Exam 7
    BMI (kg/m²)2,40528.2 ± 5.4
    Waist circumference (inches)2,38839.3 ± 5.6
    Fasting glucose (mg/dl)2,371104.3 ± 26.6
    Fasting insulin (μU/ml)2,29214.8 ± 8.7
    HOMA-IR2,2924.0 ± 3.2
    A1C (%)2,1895.7 ± 1.0
    Plasma adiponectin (μg/ml)2,01810.0 ± 6.1
  • HOMA-IR, homeostasis model insulin resistance calculated by [fasting glucose × fasting insulin]/22.5.