TABLE 2

Association of candidate SNP loci with type 2 diabetes

SNPGeneP*Odds ratio (95% CI)
rs4402960IGF2BP20.000091.368 (1.169-1.600)
rs10811661CDKN2A/B0.00241.255 (1.084-1.454)
rs5219KCNJ110.00341.254 (1.078-1.459)
rs1111875HHEX0.00641.243 (1.063-1.453)
rs7923837HHEX0.37731.083 (0.907-1.293)
rs13266634SLC30A80.00731.225 (1.056-1.420)
rs7756992CDKAL10.03631.164 (1.010–1.342)
rs9939609FTO0.23761.114 (0.931-1.332)
rs8050136FTO0.35201.089 (0.910–1.302)
rs1801282PPARG0.41370.843 (0.559-1.270)
rs7480010LOC3877610.43931.073 (0.898-1.281)
rs1113132EXT20.47281.056 (0.910-1.225)
rs11037909EXT20.53651.048 (0.903-1.216)
rs9300039418719420.69661.034 (0.874-1.222)
  • * P value is calculated on logistic regression with additive model (sex, age, BMI adjusted, and BMI were log transformed for the analysis);

  • r2 = 0.50 (this study), 0.346 (HapMap-JPT), and 0.698 (HapMap-CEU), respectively.

  • Position on the chromosome is indicated.