Association of the SNP loci with BMI in control subjects
| SNP/gene | Genotype (number of subjects)/BMI* | P | ||
|---|---|---|---|---|
| rs9939609 | TT (676) | AT (331) | AA (37) | |
| FTO | 22.2 (21.9–22.4) | 23.0 (22.7–23.4) | 23.1 (22.5–23.8) | 0.0271 |
| rs8050136 | CC (678) | CA (331) | AA (35) | |
| FTO | 22.2 (22.0–22.4) | 23.0 (22.7–23.3) | 23.2 (22.5–23.9) | 0.0436 |
| rs7923837 | AA (653) | AG (333) | GG (46) | |
| HHEX | 22.4 (22.2–22.6) | 22.5 (22.2–22.8) | 22.7 (21.9–23.5) | 0.032 |
| rs1111875 | TT (529) | CT (419) | CC (84) | |
| HHEX | 22.5 (22.2–22.7) | 22.5 (22.2–22.7) | 22.3 (21.7–22.9) | 0.05 |
| rs5219 | CC (421) | CT (509) | TT (118) | |
| KCNJ11 Glu23Lys | 22.4 (22.1–22.7) | 22.6 (22.3–22.8) | 22.1 (21.6–22.6) | 0.0777 |
| rs1801282 | CC (2) | CG (53) | GG (995) | |
| PPARG Pro12Ala | 24.4 | 23.1 (22.4–23.9) | 22.4 (22.2–22.6) | 0.1039 |
| rs11037909 | CC (141) | CT (471) | TT (425) | |
| EXT2 | 22.4 (21.9–22.9) | 22.7 (22.4–22.9) | 22.3 (22.0–22.6) | 0.1243 |
| rs1113132 | CC (143) | CG (467) | GG (427) | |
| EXT2 | 22.4 (21.9–22.9) | 22.6 (22.4–22.9) | 22.3 (22.0–22.6) | 0.1315 |
| rs9300039 | AA (68) | AC (370) | CC (592) | |
| 41871942† | 22.7 (21.9–23.5) | 22.5 (22.2–22.8) | 22.4 (22.2–22.6) | 0.4153 |
| rs13266634 | TT (173) | CT (491) | CC (376) | |
| SLC30A8 | 22.6 (22.1–23.1) | 22.5 (22.2–22.7) | 22.4 (22.2–22.7) | 0.6014 |
| rs10811661 | CC (200) | CT (518) | TT (326) | |
| CDKN2A/B | 22.3 (21.9–22.7) | 22.5 (22.2–22.7) | 22.5 (22.2–22.8) | 0.6185 |
| rs7480010 | AA (684) | AG (317) | GG (42) | |
| LOC387761 | 22.4 (22.1–22.6) | 22.8 (22.5–23.1) | 22.3 (21.5–23.2) | 0.7183 |
| rs7756992 | AA (289) | AG (508) | GG (236) | |
| CDKAL1 | 22.4 (22.0–22.7) | 22.6 (22.4–22.9) | 22.3 (22.0–22.7) | 0.7985 |
| rs4402960 | GG (520) | GT (433) | TT (88) | |
| IGF2BP2 | 22.5 (22.3–22.8) | 22.4 (22.1–22.7) | 22.5 (21.8–23.1) | 0.9313 |
* Data are presented as geometric means, and values for 95% CI are in parentheses;
† position on the chromosome is indicated.