TABLE 4

The comparison of risk allele frequency and population-attributable risk (PAR) between Japanese and white populations

SNPGeneRisk allele frequency (%)P*PAR (%)
This studyWhite populationsThis studyWhite populations
rs4402960IGF2BP229.331.30.143911.14.8
rs10811661CDKN2A/B56.184.12.2 × 10−18313.418.1
rs5219KCNJ1135.546.41.9 × 10−169.15.7
rs1111875HHEX28.457.73.2 × 10−1467.319.0
rs7923837HHEX20.662.33.6 × 10−21820.0
rs13266634SLC30A860.063.40.009712.514.6
rs7756992CDKAL147.423.23.0 × 10−1147.76.1
rs9939609FTO19.438.51.3 × 10−19
rs8050136FTO19.339.06.0 × 10−67
rs1801282PPARG97.382.44.2 × 10−6314.2
rs7480010LOC38776119.130.19.5 × 10−218.0
rs1113132EXT263.673.31.8 × 10−1619.0
rs11037909EXT263.672.92.6 × 10−1425.0
rs93000394187194275.389.22.5 × 10−4630.6
  • * P values for χ2 test for genotype distribution (2 × 3 contingency table);

  • combined data from WTCCC, UKRS, FUSION, French, and Icelandic studies;

  • position on the chromosome is indicated.