Table 1

Protein networks identified by pathway analysis

Proteins in networkScoreFocus proteinTop functions
1ACTN4, RAGE, BTC, CCL2, CCL8, CCL11, CCL18, CCR2, CD53, CXCL1, CXCL10, ELK3, HGF, ICAM3, IGFBP4, IL15, IL16, IL18RAP, IL1RN, IL28A, IL2RA, IL6ST, ITGAD, ITGB1 ITGB2, MCPT4, NOS2A, PLA2G10, PPBP, PRDX4, PTGS2 RNASE3, SCGB1A1, YARS5622Immune response cellular movement, hematological system development and function
2ANG, AXL, BTC, BTN3A3 C10ORF10, CCL8, CHST4, CIB2, CXCL13, DGCR6, FCGR1B, FCGR1C, GSTA4, H60, HRSP12, ICAM3, IFNG, IL6, IL1A, IL1F6, IL1F9, JUN, MAPK14, MYHS, NTF3, RAET1B, SLC28A1, SLC28A2, SPTA1, STAT3, TNF, TNFSF14, TNN, TRAFD1, UBR2148Cell-to-cell signaling and hematological system development and function