TABLE 2

Risk of different HLA genotypes for being associated with type 1 and type 2 diabetes compared with LADA

HLA genotypeLADA (%)Type 1 diabetes
Type 2 diabetes
Control (%)
%OR95% CIP%OR95% CIP
*0201/X29240.80.5–1.20.24311.10.7–1.70.6836*
*0302/X29331.20.8–1.90.32210.60.4–1.00.0516*
*0201/*030227361.51.0–2.30.066.90.20.1–0.4<1 × 10−66.0*
*0602/X*0603/X8.13.20.30.1–0.70.003253.51.8–6.90.000223*
  • X refers to a homozygous allele or any allele other than 0201, 0302, or 0602(3). The odds ratios (OR) refer to the risk of having type 1 and type 2 diabetes vs. LADA (OR = 1) if carrying the specific genotype, using logistic regression analysis adjusting for BMI, age, and sex.

  • *

    * Genotype frequencies of 216 Swedish control subjects (20).