TABLE 3

Frequency (%) of single nucleotide polymorphisms in the INS VNTR, PTPN22, and TCF7L2 genes in the Swedish and Finnish cohorts

Gene/single nucleotide polymorphismGenotypeControl subjects
Type 1 diabeticLADA
Type 2 diabetic
SwedishFinnishSwedishSwedishFinnishSwedishFinnish
INS VNTR/rs689AA54.873.469.0
ATTT45.226.631.0
P =3 × 10−140.001
INS VNTR/rs3842755CC65.079.376.0
CAAA35.020.724.0
P =3 × 10−100.008
PTPN22/rs2476601CC82.968.071.376.9
CTTT17.132.029.723.1
P =1 × 10−10*0.002*0.008*
TCF7L2/rs7903146CC55.268.456.747.257.745.959.5
CTTT44.831.643.352.842.354.140.5
P =0.550.03*3 × 10−7*
TCF7L2/rs12255372GG52.470.155.546.758.448.761.3
GTTT47.629.944.553.341.651.338.7
P =0.160.09*0.003*
  • Differences in genotype frequency were tested by χ2 tests comparing diabetic groups with the control group.

  • *

    * P values corrected for multiple comparisons.