TABLE 1

Baseline characteristics of normal and diabetic subjects

Control subjectsDiabetic subjects
n2227
Sex (male/female)12/1014/13
Age (years)50.5 ± 2.551.3 ± 2.6
BMI (kg/m2)28.5 ± 3.129.5 ± 3.3
Fasting glucose (mmol/l)4.5 ± 0.37.8 ± 2.2*
A1C (%)4.8 ± 0.27.7 ± 0.3*
Resting systolic blood pressure (mmHg)117.3 ± 5.5123.4 ± 6.4
Resting diastolic blood pressure (mmHg)77.5 ± 2.280.2 ± 3.6
Total cholesterol (mmol/l)4.5 ± 0.65.1 ± 0.8
Triglycerides (mmol/l)0.9 ± 0.21.2 ± 0.4
HDL cholesterol (mmol/l)1.4 ± 0.21.2 ± 0.3
LDL cholesterol (mmol/l)2.5 ± 0.32.6 ± 0.4
FMD (%)11.7 ± 0.75.9 ± 0.6*
Nitrotyrosine (μmol/l)0.24 ± 0.50.52 ± 0.3*
  • Data are means ± SEM unless otherwise indicated.

  • *

    * P < 0.001 vs. control subjects.