TABLE 2

Circulating arterialized metabolite concentrations during baseline and isoprenaline infusion in lean and obese subjects

Lean
Obese
BaselineISOΔBaselineISOΔ
n1310101077
TAG (μmol/l)701 ± 66648 ± 64*−46 ± 231,464 ± 1901,667 ± 217*112 ± 44
FFA (μmol/l)661 ± 41942 ± 53*271 ± 46638 ± 421,124 ± 82*469 ± 82
Glycerol (μmol/l)102 ± 5118 ± 7*15 ± 5106 ± 4147 ± 10*44 ± 9
Glycerol Ra (μmol/min)199 ± 12311 ± 28*109 ± 13220 ± 15391 ± 30*172 ± 19
Glycerol Ra/FFM (μmol · kg−1 FFM · min−1)3.4 ± 0.25.5 ± 0.5*2.0 ± 0.53.3 ± 0.35.8 ± 0.6*2.5 ± 0.5
Glucose (mmol/l)5.3 ± 0.15.4 ± 0.10.14 ± 0.065.5 ± 0.25.4 ± 0.1−0.12 ± 0.10
Insulin (mU/l)7.2 ± 0.610.7 ± 0.9*3.4 ± 0.613.6 ± 1.024.0 ± 2.3*10.6 ± 1.5
Lactate (mmol/l)0.61 ± 0.040.72 ± 0.030.09 ± 0.040.98 ± 0.110.99 ± 0.060.05 ± 0.07
  • Data are means ± SE.

  • *

    * P < 0.05 ISO vs. baseline.

  • P < 0.05 obese vs. lean.

  • P < 0.05 change (Δ) from baseline obese vs. lean.