TABLE 2

Type 1 diabetes association analysis

NameMAMAFEigenstrat χ2Z CaCo*Z TDTZ (P)Age-at-onset F (P)§
rs2197423A0.1160.364−0.604−0.705−0.912 (0.362)0.648 (0.523)
rs4402960A0.3300.354−0.595−1.732−1.546 (0.122)0.512 (0.600)
rs10012946A0.3620.103−0.321−0.332−0.458 (0.647)1.048 (0.371)
rs4712523C0.3400.898−0.948−0.045−0.769 (0.442)0.756 (0.470)
rs7756992C0.2960.040−0.2010.105−0.091 (0.927)0.781 (0.458)
rs13266634A0.2920.624−0.790−0.249−0.773 (0.440)0.429 (0.652)
rs1412829C0.3701.5721.254−0.3270.775 (0.438)0.614 (0.542)
rs2383208C0.1762.3121.5210.4451.466 (0.143)0.159 (0.853)
rs1111875A0.3920.0820.2870.0000.224 (0.823)0.549 (0.578)
rs7923837A0.3700.0350.1880.6170.532 (0.595)0.421 (0.656)
rs5215C0.3472.9461.7160.6511.747 (0.081)0.430 (0.651)
rs8050136A0.3970.4580.6770.3380.740 (0.459)0.255 (0.775)
rs7501939A0.3960.1540.3920.0000.306 (0.759)0.186 (0.906)
  • *

    * Z score of the case-control cohort.

  • Z score of the family cohort.

  • Combined Z value and P value.

  • §

    § One-way ANOVA test of age-at-onset difference of three genotypes. MA, minor allele; MAF, minor allele frequency.