TABLE 4

Effect of ARC, PVN, and i3vt GLP-1 on basal glucose production and uptake

SalineARC GLP-1i3vt GLP-1GLP-1 plus glibenclamide
Glucose production (μmol · kg−1 · min−1)
    Basal37 ± 442 ± 641 ± 433 ± 4
    ICV infusion34 ± 335 ± 340 ± 430 ± 3
Glucose uptake (μmol · kg−1 · min−1)
    Basal35 ± 542 ± 638 ± 233 ± 4
    ICV infusion31 ± 235 ± 336 ± 239 ± 3
  • Data are means ± SE. There were no significant effects of intra-ARC or i3vt GLP-1 on glucose production or uptake under basal conditions.