TABLE 1

Body, kidney, and heart weights at death

Age (months)
ANOVA
1361218AgeGroupInteraction
Body weight (g)CMO164 ± 5435 ± 16518 ± 10596 ± 17730 ± 22
n86999
DMO161 ± 24441 ± 18568 ± 20*723 ± 17731 ± 22P < 0.0001P = 0.0002P = 0.0009
n8699
Kidney weight (mg)/body weight (g)CMO5.2 ± 0.33.1 ± 0.12.4 ± 0.42.3 ± 0.32.9 ± 0.1
n86999
DMO4.4 ± 0.22.7 ± 0.33.3 ± 0.12.2 ± 0.12.9 ± 0.1P < 0.0001P = 0.5673P = 0.0021
n86999
Heart weight (mg)/body weight (g)CMO5.6 ± 0.33.9 ± 0.22.8 ± 0.43.9 ± 0.13.2 ± 0.9
n86999
DMO5.5 ± 0.43.2 ± 0.33.5 ± 0.13.4 ± 0.13.0 ± 0.2P < 0.0001P = 0.6038P = 0.0919
n86999
  • Data are means ± SE for n animals issued from two or three litters. CMO, control mother offspring; DMO, diabetic mother offspring. Two-way ANOVA with age and group effects. Comparisons are made between CMO and DMO at the same age (unpaired t test,

  • *

    * P < 0.05;

  • P < 0.001).