TABLE 3

Familial risk of proliferative retinopathy

VariableOR (95% CI)B (SE)P value
PDR status of proband (yes/no)2.76 (1.25–6.11)1.02 (0.40)0.01
MAP (mmHg)1.03 (0.99–1.06)0.02 (0.17)0.15
A1C (%)1.33 (1.03–1.73)0.29 (0.14)0.03
Duration of diabetes (years)1.13 (1.08–1.17)0.12 (0.02)<0.001
Men1.12 (0.51–2.45)0.12 (0.40)0.8
  • The presence of proliferative retinopathy in the proband was used as risk factor for proliferative retinopathy in 182 siblings of 168 probands in a logistic regression analysis. MAP, mean arterial blood pressure; PDR, proliferative diabetic retinopathy.