TABLE 1

Metabolic outcome 6 months after islet cell transplantation

At posttransplant month 6
P*
Insulin independentInsulin dependent
C-peptide positive (n)15/1514/15
C-peptide (ng/ml)2.3 (1.9–3.0)1.0 (0.4–1.2)<0.001
Fasting glycemia
    Mean (mg/dl)127 (115–135)132 (127–153)0.12
    CVfg (%)9 (8–10)19 (15–39)<0.001
A1C (%)6.1 (5.8–6.4)6.1 (5.7–6.7)0.66
Insulin dose (IU · kg−1 · day−1)00.27 (0.20–0.46)<0.001
Percentage of baseline insulin dose (%)043 (34–69)<0.001
  • Data are medians (IQR). Fasting glycemia was measured at home, and within-subject variation of fasted glycemia (CVfg) was calculated during the preceding month.

  • *Statistical analysis was done with Mann-Whitney U test.