TABLE 3

Comparison of clinical characteristics for RACED participants with lower (≤100) or higher (>100) CAC according to VADT treatment assignment

Lower CAC
PHigher CAC
P
StandardIntensiveStandardIntensive
n62529790
Age (years)57 ± 957 ± 90.7464 ± 964 ± 90.90
NHW58480.2975700.42
Duration of diabetes (years)10.2 ± 7.29.4 ± 7.80.5713.12 ± 7.213.9 ± 7.80.49
BMI (kg/m2)31.8 ± 4.030.9 ± 4.60.2831.6 ± 4.531.5 ± 4.30.92
History of CVD1660.0854540.91
Current smoker18150.7413140.84
History of hypertension65750.2386840.72
SBP (mmHg)133 ± 18131 ± 160.62132 ± 18130 ± 170.39
DBP (mmHg)78 ± 1079 ± 110.5673 ± 973 ± 100.88
A1C9.6 ± 1.49.5 ± 1.50.889.1 ± 1.39.1 ± 1.40.90
Total cholesterol (mmol/l)4.84 ± 1.164.94 ± 1.110.704.50 ± 0.784.53 ± 0.920.83
HDL cholesterol (mmol/l)0.96 ± 0.281.06 ± 0.310.120.89 ± 0.251.06 ± 0.210.11
LDL cholesterol (mmol/l)2.79 ± 0.932.90 ± 0.880.522.57 ± 0.672.68 ± 0.720.28
Triglycerides (mmol/l)2.40 ± 1.702.05 ± 1.000.212.53 ± 1.612.03 ± 1.360.02
Statin use52540.8161700.19
TZD use1380.3711110.96
ASA use87850.7186870.83
BP medication89850.5293920.88
CAC (Agatston units)20 ± 2618 ± 260.641,106 ± 1,3841,106 ± 1,1460.99
  • Data are means ± SD or percent unless otherwise indicated. ASA, aspirin; BP, blood pressure; DBP, diastolic blood pressure; NHW, non-Hispanic white; SBP, systolic blood pressure; TZD, thiazolidinedione. P values are from independent-samples t tests or Wilcoxon or χ2 tests, as appropriate.