TABLE 4

Metabolic parameters from hyperinsulinemic-euglycemic clamps in rats

Low-fat dietMCFAsLCFAs
GIR (mg · kg−1 · min−1)38.4 ± 1.631.4 ± 1.3*21.5 ± 1.6*
Rd (mg · kg−1 · min−1)36.9 ± 1.334.3 ± 1.125.9 ± 1.9*
HGO (mg · kg−1 · min−1)−1.5 ± 0.633.0 ± 1.1*4.3 ± 0.4*
Rǵ (red quadriceps)29.4 ± 2.026.5 ± 1.816.9 ± 2.7*
Rǵ (red gastrocnemius)29.7 ± 2.826.8 ± 1.417.6 ± 0.8*
Rǵ (white gastrocnemius)7.1 ± 0.69.0 ± 0.6*5.4 ± 0.4*
Rǵ (epididymal fat)1.8 ± 0.22.2 ± 0.21.0 ± 0.1*
  • Data are means ± SE for n = 5–7 animals. Plasma levels of glucose and insulin were similar for all groups during the clamp (data not shown).

  • *P < 0.01 vs. low fat;

  • P < 0.01 vs. MCFA. Rǵ, insulin-stimulated 3H-2-deoxyglucose uptake in skeletal muscle or adipose tissue during the clamp (μmol · 100 g−1 · min−1).