TABLE 1

Characteristics of subjects enrolled in North America and the U.K. who contributed an evaluable specimen

North America
U.K.
DiabetesNormalDiabetesNormal
n35592931
Age (years)15.0 ± 3.9826.5 ± 5.6524.2 ± 6.624.7 ± 5.5
Sex (male)22 (62.9)26 (44.1)19 (65.5)13 (41.9)
Type 1 diabetes duration (months)6.4 ± 3.053.3 ± 3.88
Whites (%)79.486.496.690.3
Collections (%)661135158
    1 only35592931
    2 only31542227
Days between collections
    2–78 (25.8)18 (33.3)5 (22.7)14 (51.9)
    8–1414 (45.2)15 (27.8)9 (40.9)7 (27.9)
    15–214 (12.9)9 (16.7)6 (27.3)2 (7.4)
    21–285 (16.1)12 (22.2)2 (9.1)4 (14.8)
Autoantibody positive
    ICA51223 (65.7)0 (0)14 (50)0 (0)
    GAD6522 (62.9)0 (0)20 (71.4)0 (0)
    ICA25 (71.4)5 (8.6)13 (46.4)0 (0)
    One7 (20)5 (8.6)7 (24.1)0 (0)
    Two or more24 (68.6)0 (0)15 (51.7)0 (0)
HLA type
    DR37 (20)16 (27.1)4 (13.8)11 (35.5)
    DR414 (40)23 (39.0)16 (55.2)17 (54.8)
    DR3/411 (31.4)9 (15.3)9 (31)3 (9.7)
    Neither3 (8.6)11 (18.6)
  • Data are means ± SD and n (%).