Table 1

Progressors remaining ICA negative during the pre-diabetic phase

HLA-DQB1Age (years)
Delay (years)
DAA status
SeroconversionLast visitDiagnosisLast visit to diagnosisPre-diabeticAt diagnosis
High risk (*02/*0302)
    Female0.980.981.340.36IAAICA, IAA, GADA
    Female1.001.400.40NegativeICA, IAA, GADA
    Female0.951.511.690.18IAA, GADAICA, IAA, GADA
    Female1.073.252.18NegativeICA, IAA, GADA
    Female4.004.330.33NegativeSample not available
    Female1.585.644.06NegativeAll four DAA
    Female7.5911.994.40NegativeICA, GADA, IA-2A
    Male0.961.620.65NegativeICA, IAA
    Male2.967.704.74NegativeICA, GADA, IA-2A
    Male2.518.746.23NegativeAll four DAA
Moderate risk (*0302/x)
    Female0.500.760.970.21IAAIAA, GADA
    Female0.770.771.080.31IAA, GADAAll four DAA
    Female0.990.991.470.48IAAICA, IAA
    Female0.252.131.88NegativeICA, IAA, GADA
    Female0.273.062.79NegativeAll four DAA
    Female2.475.963.49NegativeAll four DAA
    Female3.086.403.32NegativeICA, IAA, IA-2A
    Female3.026.573.55NegativeGADA
    Female4.014.018.184.17GADAICA, GADA, IA-2A
    Female0.326.245.92NegativeICA
    Male1.122.144.722.58IAAICA, IAA, IA-2A
    Male1.021.025.414.39IAASample not available
    Male1.037.156.12NegativeICA, IA-2A
    Male2.532.532.700.17IAA, IA-2AICA, IAA, IA-2A
    Male0.790.790.870.08IAA, GADAIAA, GADA
  • x, nonprotective HLA allele.