Indexes of STZ-induced diabetes over 24-week time period
| Experimental group (n) | Body wt (g) | Terminal blood glucose levels (mmol/l) | Motor nerve conduction velocity (m/s) | Sensory nerve conduction velocity (m/s) | |
|---|---|---|---|---|---|
| Start | End | ||||
| Control 0 | 231 ± 10 | 231 ± 10 | n.t. | n.t. | n.t. |
| Control 24 weeks | 239 ± 5 | 361 ± 53 | n.t. | 58.7 ± 9.2 | 57 ± 4.8 |
| STZ 3 weeks | 233 ± 7 | 215 ± 21 | 26 ± 3.7 | n.t. | n.t. |
| STZ 6 weeks | 242 ± 10 | 257 ± 15 | 26.9 ± 1.4 | n.t. | n.t. |
| STZ 9 weeks | 242 ± 17 | 271 ± 27 | 25.4 ± 2.9 | n.t. | n.t. |
| STZ 12 weeks | 233 ± 13 | 264 ± 41 | 21.5 ± 7.6 | n.t. | n.t. |
| STZ 24 weeks | 233 ± 16 | 319 ± 55 | 23.3 ± 7.9 | 43.2 ± 5.4* | 45.5 ± 3.9* |
Data are means ± SD unless otherwise indicated.
*P < 0.005: t test, control vs. diabetic nerve conduction velocity at 24 weeks. n.t. = not tested.