TABLE 1

Genes induced by both palmitate and linoleate in human myotubes

Gene symbolUniGene IDFold-change by palmitateFold-change by linoleate
Angiopoietin-like 4ANGPTL4Hs0.961350.433.5
Granulocyte colony-stimulating factorCSF3Hs0.223311.33.48
Pyruvate dehydrogenase kinase 4PDK4Hs0.83648.067.89
BiglycanBGNHs0.8216.772.45
AdipophilinADFPHs0.34165.665.98
Signal-induced proliferation-associated protein 1SIPA1Hs0.5304775.394.44
ElastinELNHs0.2524184.342.10
Protocadherin γ A12PCDHGA12-3.862.27
Spermine oxidaseSMOXHs0.4333373.733.81
Insulin-like growth factor-binding protein 4IGFBP4Hs0.4629983.512.58
myc-associated zinc finger proteinMAZHs0.5490523.482.39
LDL receptor-related protein 1LRP1Hs0.1627573.472.52
Heparan sulfate proteoglycan 2HSPG2Hs0.5504783.422.46
Collagen α3(V) chainCOL5A3Hs0.2353683.272.66
Brain-specific angiogenesis inhibitor 2BAI2Hs0.5241383.252.64
Xaa-Pro aminopeptidase 2XPNPEP2Hs0.1704993.202.33
Transforming growth factor β1TGFB1Hs0.11033.162.01
CLIP-170-related 59 kDa proteinCLIPR-59Hs0.4665392.982.25
Zinc finger protein 580ZNF580Hs0.943922.812.00
VitronectinVTNHs0.22572.712.03
Glucocorticoid receptor DNA-binding factor 1GRLF1Hs0.5094472.642.43
Nucleobindin 1NUCB1Hs0.5155242.622.17
Hyaluronan synthase 1HAS1Hs0.576972.622.04
Zinc and ring finger 1ZNRF1Hs0.4272842.602.16
Inositol monophosphatase 2IMPA2Hs0.3679922.572.41
Endothelin B receptorEDNRBHs0.820022.512.50
SH3 domain GRB2-like protein B2SH3GLB2Hs0.4602382.502.83
Meteorin, glial cell differentiation regulator-likeMETRNLHs0.5146152.452.11
SBF1 proteinSBF1Hs0.2802022.352.13
Glucosidase 2 β-subunitPRKCSHHs0.5126402.352.04
Mitogen-activated protein kinase 7MAPK7Hs0.1501362.312.06
Replication initiator 1REPIN1Hs0.5212892.202.08
fos-like antigen 1FOSL1Hs0.2835652.142.06
5′-TG-3′ interacting factorTGIFHs0.3735502.072.16
KIAA0467 proteinKIAA0467Hs0.3019432.032.19
  • Cells were treated for 20 h with 1.25% BSA for control or 0.5 mmol/l LCFA (changes ≥2-fold, LCFA vs. BSA).