TABLE 5

Cofactors by the rs2289669 polymorphism

GGGAAA
Sex (male)18 (50)22 (38)7 (33)
Age (years)75.3 ± 7.077.9 ± 6.575.6 ± 6.1
A1C level before start (%)8.3 ± 0.98.3 ± 1.48.4 ± 1.1
Prescribed metformin dose (mg)853 ± 476662 ± 262757 ± 320
Sulfonylurea use (%)22 (61)33 (57)13 (62)
Change in sulfonylurea dose (DDD)*−0.01 ± 0.53−0.17 ± 0.61−0.27 ± 0.52
Time from diabetes diagnosis (years)5.5 ± 4.45.6 ± 4.84.7 ± 3.7
Estimated glomerular filtration rate (ml/min)74 ± 1968 ± 1768 ± 14
BMI (kg/m2)28.9 ± 3.928.1 ± 3.827.6 ± 3.2
  • Data are means ± SD or n (%).

  • *

    * P = 0.08 for trend. DDD, defined daily dose.