TABLE 1

Baseline characteristics of subjects with type 2 diabetes of the Casale Monferrato Study, by CRP values

CRP tertiles
P
<1.6 mg/l1.6–4.4 mg/l>4.4 mg/l
n759834788
Men434 (57.2)422 (50.6)328 (41.6)<0.0001
Age (years)67.1 ± 10.668.1 ± 9.967.7 ± 10.70.16
Duration of diabetes (years)11.2 ± 8.410.3 ± 7.410.5 ± 8.00.06
BMI (kg/m2)26.7 ± 4.028.7 ± 4.530.6 ± 6.0<0.0001
Waist circumference (cm)93.9 ± 11.098.8 ± 11.6101.9 ± 12.5<0.0001
Systolic blood pressure (mmHg)143.2 ± 15.9146.7 ± 15.9147.1 ± 17.0<0.0001
Diastolic blood pressure (mmHg)81.8 ± 7.982.2 ± 8.183.4 ± 8.5<0.0001
Hypertension653 (86.3)740 (89.1)718 (91.1)0.01
Glucose (mg/dl)163.0 ± 48.7172.9 ± 52.9182.6 ± 61.0<0.0001
A1C (%)6.8 ± 1.76.9 ± 1.77.3 ± 1.9<0.0001
Total cholesterol (mg/dl)205.6 ± 40.6213.8 ± 38.7215.4 ± 40.6<0.0001
LDL cholesterol (mg/dl)123.0 ± 35.5128.7 ± 31.9130.9 ± 35.0<0.0001
HDL cholesterol (mg/dl)57.2 ± 16.154.5 ± 14.852.7 ± 14.2<0.0001
Triglycerides (mg/dl)113 (79–155)134 (96–178)141 (101–192)<0.0001
ApoA1 (mg/dl)160.5 ± 39.5154.7 ± 37.8147.1 ± 38.4<0.0001
ApoB (mg/dl)96.1 ± 26.0103.5 ± 25.9106.7 ± 27.4<0.0001
ApoB/apoA10.65 ± 0.310.72 ± 0.310.79 ± 0.37<0.0001
Creatinine (mg/dl)0.84 (0.70–0.97)0.84 (0.71–0.98)0.86 (0.69–1.02)0.16
Fibrinogen (g/l)353.5 ± 66.5371.8 ± 68.9413.1 ± 96.2<0.0001
Uric acid (mg/dl)5.22 ± 1.445.57 ± 1.556.08 ± 2.53<0.0001
AER (μg/min)10.9 (4.0–22.6)13.1 (4.6–27.7)16.3 (4.9–40.7)<0.0001
    20–200137 (22.9)169 (25.7)184 (29.8)<0.0001
    >20024 (4.0)31 (4.7)46 (7.5)
CVD136 (17.9)180 (21.6)194 (24.6)0.006
Smoking
    Former smoker243 (32.9)236 (29.7)221 (28.9)0.28
    Smoker112 (15.2)130 (16.3)109 (14.2)
Glucose-lowering treatment
    Diet128 (17.0)135 (16.4)102 (13.1)0.21
    Oral drugs549 (73.0)605 (73.7)585 (75.4)
    Insulin75 (10.0)81 (9.9)89 (11.5)
Statins163 (21.5)163 (19.5)151 (19.2)0.77
  • Data are means ± SD, n (%), or geometric means (95% CI).