TABLE 1

Spearman correlation coefficients between surrogate indexes of β-cell function and insulin release during the first phase (0–10 min) and second phase (10–60 min) and total (0–60 min) during an IVGTT

β-Cell function indexesInsulin release during an IVGTT
First phaseSecond phaseTotal
HOMA-β0.5680.6450.663
Insulinogenic index0.5790.4690.541
InsAUC30/GluAUC300.6660.7070.743
ΔInsAUC120/ΔGluAUC1200.3750.4090.405
InsAUC120/GluAUC1200.6480.7500.775
First-phase Stumvoll0.6510.6630.702
Second-phase Stumvoll0.6620.6920.730
Fasting insulin0.5480.7470.735
Insulin at 30 min of an OGTT0.6150.6910.715
Insulin at 120 min of an OGTT0.4290.6730.645
Insulin AUC during an OGTT0.5580.7700.776
  • P < 0.001 for all correlation coefficients. Indexes of β-cell function were calculated as described previously: HOMA-β(30), insulinogenic index (31), ΔInsAUC120/ΔGluAUC120 (25), InsAUC120/GluAUC120 (31), first phase Stumvoll (32), and second phase Stumvoll (32). InsAUC30/GluAUC30 = (insulin at 0 min + insulin at 30 min of an OGTT)/(glucose at 0 min + glucose at 30 min of an OGTT).