TABLE 1

Total and arch plaque area was quantitated as a percentage area of aorta stained red with Sudan IV in control apoE KO, diabetic apoE KO, and previously hyperglycemic apoE KO mice

nTotalArchThoracicAbdominal
Control apoE KO (NG→NG)103.0 ± 0.58.0 ± 0.51.2 ± 0.31.1 ± 0.3
Diabetic apoE KO (HG→HG)1013.0 ± 1.0*24.4 ± 1.0*8.7 ± 1.0*8.5 ± 0.7*
Previously hyperglycemic apoE KO (HG→NG)611.4 ± 1.9*21.3 ± 2.1*8.0 ± 2.7*8.2 ± 1.8*
  • Data are means ± SE.

  • *P < 0.05 compared with the control apoE KO group.