TABLE 2

mRNA expression of NFκB-p65, MCP-1, and VCAM in control apoE KO, diabetic apoE KO, and previously hyperglycemic apoE KO mice

nNFκB-p65MCP-1VCAM-1
Control apoE KO (NG→NG)51.0 ± 0.21.1 ± 0.21.0 ± 0.2
Diabetic apoE KO (HG→HG)52.5 ± 0.9*3.2 ± 1.1*3.2 ± 0.5*
Previously hyperglycemic apoE KO (HG→NG)42.7 ± 1.1*3.7 ± 0.9*1.9 ± 0.06*
  • Data are means ± SE.

  • *P < 0.05 compared with control apoE KO group;

  • P < 0.05 compared with diabetic apoE KO group.