TABLE 1

Body composition of 4-month-old mice after being weaned onto HFD or standard diet

nWeight (g)
FatLeanBody
Male
    Mstn+/+ genotype
        HFD108.2 ± 1.39*21.9 ± 0.69*32.3 ± 1.37*
        Standard diet73.2 ± 0.5321.7 ± 1.2128.3 ± 1.45
    Mstn+/Ln genotype
        HFD346.4 ± 0.43*26.5 ± 0.43*36.3 ± 0.46*
        Standard diet53.1 ± 0.3323.8 ± 0.4730.3 ± 0.68
    MstnLn/Ln genotype
        HFD280.70 ± 0.11*33.6 ± 0.53*36.9 ± 0.54*
        Standard diet80.45 ± 0.0827.2 ± 0.6829.5 ± 0.68
Female
    Mstn+/+ genotype
        HFD65.0 ± 0.4718.2 ± 0.2825.7 ± 0.61
        Standard diet82.0 ± 0.0717.7 ± 0.3222.1 ± 0.42
    Mstn+/Ln genotype
        HFD154.9 ± 0.3318.8 ± 0.2826.2 ± 0.51
        Standard diet92.3 ± 0.1419.1 ± 0.3623.6 ± 0.47
    MstnLn/Ln genotype
        HFD81.99 ± 0.1424.3 ± 0.4428.2 ± 0.41
        Standard diet61.21 ± 0.0622.1 ± 0.4124.9 ± 0.46
  • Data are means ± SE.

  • *P < 0.05 vs. HFD female mice;

  • P < 0.05;

  • P < 0.01 vs. mice of the same sex and genotype on standard diet.