Numbers of total and Ki-67–positive nuclei in islets

Counted islets per animalCounted nuclei per animalNuclei per isletProportion of Ki-67–positive nuclei per islet (%)
Wild type686,297 ± 664.593 ± 7.61.10 ± 0.08
Transgenic605,291 ± 567.789 ± 9.71.16 ± 0.13
  • Data are means ± SE of values from four animals from each genotype. Pancreatic sections were immunostained with the anti–Ki-67 antibody followed by counterstaining with hematoxylin as shown inFig. 3I. Numbers of all nuclei and of Ki-67–positive nuclei in the islets of wild-type and transgenic mice were counted.