TABLE 2

HLA-DR and -DQ in type 1 diabetic responders and nonresponders

nDR3DR4DR3/DR4DQ2DQ3
Nonresponders224159144164
Responders205095 (P = 0.01)45 (P = 0.04)50 (P = 0.75)95 (P = 0.02)
  • Data are % unless otherwise indicated. T-cell proliferation (CDI) to WP was evaluated in type 1 diabetic patients. Patients with a CDI value greater than mean + 3 SD of the control group (CDI >14.6) were classified as responders. Those below were classified as nonresponders. The percentage of individuals with the indicated HLA haplotypes in these groups was calculated.