TABLE 3

RRs of self-reported type 2 diabetes by homocysteine-lowering intervention according to other randomized treatment assignment groups in the WAFACS

SubgroupsNumber of events/number of participants (%)
RR (95% CI)
Active groupPlacebo groupAge-adjusted model*P value for interaction
Vitamin C
    Active114/1,059 (0.11)119/1,059 (0.11)0.95 (0.74–1.23)0.86
    Placebo131/1,073 (0.12)140/1,061 (0.13)0.92 (0.73–1.17)
Vitamin E
    Active132/1,067 (0.12)140/1,038 (0.13)0.91 (0.72–1.16)0.77
    Placebo113/1,065 (0.11)119/1,082 (0.11)0.96 (0.74–1.24)
β-carotene
    Active113/1,077 (0.10)128/1,040 (0.12)0.83 (0.65–1.07)0.21
    Placebo132/1,055 (0.13)131/1,080 (0.12)1.04 (0.82–1.33)
  • *Adjusted for age and two randomized assignments other than stratified groups.