TABLE 1

Clinical, hormonal, and metabolic features of women with PCOS and control subjects

PCOS (n = 14)Control subjects (n = 14)Significance
Age (years)29.5 (28–38)32.5 (29–35)NS
BMI (kg/m2)30.5 (27.8–30.9)28.8 (28–30.5)NS
WHR0.89 (0.78–0.99)0.84 (0.81–0.96)NS
Glucose (mmol/l)5.5 (4.8–6.0)4.5 (4.3–5.2)P < 0.01
Insulin (pmol/l)78.9 (42.0–91.1)57.3 (48.5–66.0)NS
HOMA-IR3.0 (2.1–3.6)2.0 (1.4–2.2)P < 0.05
Cholesterol (mmol/l)5.1 (4.1–5.7)5.0 (4.8–5.5)NS
Triglycerides (mmol/l)2.0 (1.5–2.3)0.9 (0.7–1.4)P < 0.01
Luteinizing hormone (IU/l)7.0 (6.0–10.0)6.0 (5.0–7.0)NS
Follicle-stimulating hormone (IU/l)6.0 (6.0–7.0)6.5 (5.0–8.0)NS
Prolactin (mU/l)348.0 (305.0–387.0)304.5 (211.0–322.0)NS
E2 (pmol/l)353.5 (287.0–471.0)174.5 (129.0–264.0)P < 0.01
Progesterone (nmol/l)1.6 (1.3–2.1)2.2 (1.7–2.3)NS
17-OH-P (nmol/l)2.5 (2.1–2.8)2.0 (1.2–2.3)NS
Testosterone (nmol/l)1.7 (1.5–2.1)0.8 (0.6–0.9)P < 0.01
Androstenedione (nmol/l)15.6 (14.2–16.8)6.3 (5.0–8.2)P < 0.01
DHEA-S (μmol/l)5.9 (5.4–6.6)4.5 (4.0–5.3)P < 0.05
SHBG (nmol/l)31.5 (26.7–35.2)59.0 (47.7–66.0)P < 0.01
FAI19.5 (14.5–21.2)3.9 (3.3–6.1)P < 0.01
Leptin (ng/ml)24.9 (19.7–29.0)24.1 (19.3–28.8)NS
Adiponectin (μg/ml)5.67 (4.52–7.5)6.27 (5.52–9.48)NS
Chemerin (ng/ml)6.02 (5.96–6.04)2.62 (1.96–3.23)P < 0.01
  • Data are medians (interquartile range). Group comparison by Mann-Whitney U test. FAI = Testosterone (nmol/liter)/SHBG (nmol/liter) × 100. NS = not significant. FAI, free androgen index; SHBG, sex hormone–binding globulin.