TABLE 3

Linear regression analysis of variables associated with changes in serum chemerin levels (before and after metformin treatment), Δchemerin, in PCOS subjects (n = 21)

Simple
Multiple
EstimatePEstimateP
ΔBMI (kg/m2)0.1560.500
ΔWHR0.4860.0260.2930.329
ΔGlucose (mmol/l)0.5100.018−0.3380.234
ΔInsulin (pmol/l)0.5030.020−0.3870.205
ΔHOMA-IR0.772<0.0100.6280.046
ΔCholesterol (mmol/l)0.2760.226
ΔTriglycerides (mmol/l)0.4900.0240.4560.107
ΔE2 (pmol/l)0.2400.327
ΔTestosterone (nmol/l)−0.1300.576
ΔAndrostenedione (nmol/l)0.0390.867
ΔDHEA-S (μmol/l)−0.0550.814
ΔSHBG (nmol/l)0.2360.304
ΔFAI−0.2240.330
ΔLeptin (ng/ml)−0.0030.989
ΔAdiponectin (μg/ml)0.0260.911
  • In multiple linear regression analysis, values included were WHR, glucose, insulin, HOMA-IR, and triglycerides. FAI, free androgen index; SHBG, sex hormone–binding globulin.