TABLE 1

Clinical, hormonal, and metabolic features of women with PCOS and control subjects

VariablePCOS (n = 21)Control subjects (n = 39)Significance
Age (years)28 (26.5–31.5)28 (23–32)NS
BMI (kg/m2)32.8 (29.8–36.5)29.1 (27.3–34.1)NS
WHR0.82 (0.76–0.88)0.81 (0.78–0.86)NS
Glucose (mmol/l)5.1 (4.7–5.5)4.8 (4.4–5.1)NS
Insulin (pmol/l)70.0 (54.5–94.5)41.0 (32.0–55.0)P < 0.01
HOMA-IR2.2 (2.0–3.0)1.2 (1.0–1.7)P < 0.01
Cholesterol (mmol/l)4.9 (4.1–5.3)4.3 (3.8–4.8)P < 0.05
Triglycerides (mmol/l)1.0 (0.8–1.7)0.8 (0.6–1.1)P < 0.05
LH (IU/l)7.8 (4.7–11.0)3.8 (2.7–5.4)P < 0.01
FSH (IU/l)5.2 (4.0–6.2)5.7 (4.3–7.5)NS
Testosterone (nmol/l)1.8 (1.5–2.5)1.2 (1.0–1.6)P < 0.01
Androstenedione (nmol/l)3.0 (2.3–3.8)2.6 (1.9–3.6)NS
DHEA-S (μmol/l)4.3 (2.7–5.6)6.1 (3.8–7.5)P < 0.01
SHBG (nmol/l)27.0 (20.5–41.0)45.0 (34.0–59.0)P < 0.01
FAI6.6 (4.6–9.7)3.0 (1.9–4.4)P < 0.01
SBP (mmHg)125.0 (120.0–130.0)120.0 (110.0–120.0)P < 0.01
DBP (mmHg)80.0 (75.0–80.0)75.0 (70.0–80.0)P < 0.01
IMT (mm)0.53 (0.48–0.58)0.42 (0.40–0.44)P < 0.01
hs-CRP (mg/l)3.3 (2.4–5.5)1.3 (0.5–2.5)P < 0.01
Omentin-1 (ng/ml)23.7 (20.0–27.9)27.6 (25.6–29.4)P < 0.05
  • Data are median (interquartile range). Group comparison by Mann–Whitney U test. Free androgen index (FAI) = T (nmol/l)/SHBG (nmol/l) × 100. NS = not significant; LH, luteinizing hormone; FSH, follicular stimulating hormone; DHEA-S, dehydroepiandrosterone-sulfate; SHBG, sex hormone–binding globulin; SBP, systolic blood pressure; DBP, diastolic blood pressure.