TABLE 1

Clinical and biological characteristics of obese subjects before, and 3 and 6 months after gastric surgery

After bypass
Before bypass3 months6 months
Food intake
    Food intake (kcal)1,933 ± 101A1,080 ± 87B1,355 ± 54C
Adiposity markers
    Body weight (kg)126 ± 4.2A107 ± 3.9B98 ± 3.8C
    BMI (kg/m2)47.6 ± 1.5A40.6 ± 1.3B37.1 ± 1.3C
    Adipocyte diameter (μm)116.7 ± 1.5A110.7 ± 1.0B103.3 ± 3.2C
    REE (kcal)1,814.4 ± 54.8A1,842.5 ± 53.6A1,551.1 ± 42.9B
    Fat mass %47.9 ± 1.0A44.5 ± 1.0B41.3 ± 1.2C
    Fat-free mass %50.0 ± 1.0A53.0 ± 0.9B55.9 ± 1.1C
    Leptin (ng/ml)50.8 ± 3.7A25.6 ± 2.5B24.9 ± 2.8B
Plasma glucose homeostasis and insulin sensitivity
    Glycemia (mmol/l)6.4 ± 0.5A5.1 ± 0.2B4.8 ± 0.1B
    A1C (%)6.4 ± 0.3A5.7 ± 0.1B5.8 ± 0.1B
    Insulinemia (μU/ml)17.1 ± 1.6A10.7 ± 0.9B6.9 ± 0.7C
    HOMA-IR0.88 ± 0.09A0.63 ± 0.03B0.78 ± 0.09A
    Adiponectin (μg/ml)6.4 ± 0.5A7.8 ± 0.7A8.3 ± 0.7B
Plasma lipid homeostasis
    Total cholesterol (mmol/l)4.54 ± 0.16A4.23 ± 0.16A4.34 ± 0.15A
    Triglycerides (mmol/l)1.57 ± 0.19A1.54 ± 0.17A1.48 ± 0.17A
    HDL cholesterol (mmol/l)1.22 ± 0.05A1.17 ± 0.06A1.30 ± 0.06B
Inflammatory markers
    Plasma hs-CRP (mg/dl)3.1 ± 0.8A2.5 ± 0.9B2.7 ± 0.8B
    Plasma IL-6 (pg/ml)4.4 ± 0.4A4.2 ± 0.4A3.4 ± 0.4A
    Plasma orosomucoid (g/l)1.02 ± 0.04A,B0.94 ± 0.04A0.86 ± 0.03B
  • Values are expressed as mean ± SE (n = 30). Fat mass %, fat-free mass %: values expressed as a percentage of body weight. Paired Wilcoxon stands for analyzing parameters changes between various time points. Data not sharing the same letter within a horizontal line are significantly different (P < 0.05). REE: resting energy expenditure.