TABLE 1

BMI according to genotypes and per effect allele change in BMI after age and sex adjustment

SNPPositionNearest geneEffect allele (1)Other allele (2)BMIP (additive model)Per effect allele change in BMI (β)Lower bound of one-sided 95% CI
111222Nominal PPermuted P
rs713880348533735FAIM2AG22.4 ± 0.222.0 ± 0.121.7 ± 0.10.00160.00970.350.15
rs180508119394430NPC1AG22.0 ± 0.121.9 ± 0.121.4 ± 0.30.0630.280.21−0.0047
rs649964052327178FTOAG22.1 ± 0.422.1 ± 0.121.8 ± 0.10.0230.120.290.044
rs1778231356002077MC4RCT23.1 ± 0.322.2 ± 0.121.6 ± 0.13.6 × 10−71.0 × 10−50.630.42
rs626527636492BDNFGA22.2 ± 0.121.9 ± 0.121.6 ± 0.20.00670.0380.270.093
rs1093839745023455GNPDA2GA22.6 ± 0.222.0 ± 0.121.6 ± 0.10.000160.000930.450.26
  • Data are means ± SE. Nominal P values were adjusted for age and sex, and permuted P values were further corrected for multiple testing. All P values were one-sided.