TABLE 1

Follow-up examination of endocrine and exocrine pancreas function in neonatal diabetic patients

Patient 4 (male)Patient 8 (female)Normal values
Age at follow-up examination47 months28 months
Endocrine pancreas
    C-peptide after meal (μg/l)<0.1<0.10.8–4.0
    A1C (%)8.37.74.0–6.0
    Serum glucagon (ng/l)2615915–250
Exocrine pancreas
    Fecal fat excretion (g/24h)3.53.21–3
    Stool chymotrypsin (units/g stools)5.51.5>8.4
    Stool elastase (μg/g stools)17020>200
    Serum lipase (units/l)14<78–78
    Vitamin A (μmol/l)0.71.280.50–2.40
    Vitamin D (nmol/l)N.D.28>25
    Vitamin E (μmol/l)22.115.212.0–28.0
    Vitamin K (ng/l)222260100–1,000
    Serum IGF1 (μg/l)433254–194 (male subjects);
62–125 (female subjects)