TABLE 1

Clinical and biochemical characteristics of the studied groups

LeanObeseP (obesity/PCOS)
ControlPCOSControlPCOS
n18351643
Age (years)26.33 ± 5.5624.11 ± 3.9427.44 ± 5.2725.60 ± 5.57NS
BMI (kg/m2)22.19 ± 1.9221.71 ± 1.8130.66 ± 4.3731.46 ± 4.34<0.001/NS
Waist (cm)73.72 ± 5.5072.66 ± 6.9594.13 ± 10.9594.36 ± 12.57<0.001/NS
Body fat (%)21.97 ± 5.7124.76 ± 6.8437.79 ± 9.0337.90 ± 10.84<0.001/NS
Fasting glucose (mg/dl)80.82 ± 6.2080.22 ± 8.2181.08 ± 6.9886.00 ± 7.28NS
Postload glucose (mg/dl)81.31 ± 15.4082.22 ± 15.3192.68 ± 20.2497.28 ± 23.090.0013/NS
Fasting insulin (μIU/ml)8.44 ± 3.2111.80 ± 5.9514.33 ± 5.3016.14 ± 9.58<0.001/NS
Postload insulin (μIU/ml)31.28 ± 15.9040.17 ± 25.8848.37 ± 37.3782.01 ± 92.340.014/NS
Cholesterol (mg/dl)186.68 ± 36.83181.06 ± 36.16173.25 ± 40.97185.78 ± 38.66NS
Triglycerides (mg/dl)66.92 ± 21.4470.40 ± 34.06105.83 ± 103.47103.27 ± 54.740.005/NS
HDL cholesterol (mg/dl)56.35 ± 12.7362.99 ± 13.7357.16 ± 9.0250.23 ± 9.560.013/NS
LDL cholesterol (mg/dl)117.89 ± 38.26102.89 ± 33.8094.23 ± 28.77114.70 ± 39.12NS
M/BW (mg · kg body wt−1 · min−1)8.85 ± 2.277.21 ± 2.865.91 ± 2.194.47 ± 2.37<0.001/0.003
M/FFM (mg · kg FFM−1 · min−1)11.41 ± 3.069.54 ± 3.759.64 ± 3.337.07 ± 3.230.003/0.002
hsIL-6 (pg/ml)0.74 ± 0.730.85 ± 0.830.85 ± 0.371.16 ± 0.740.007/NS
sIL-6R (ng/ml)48.14 ± 21.9437.53 ± 14.6546.15 ± 13.0336.55 ± 11.96NS/0.003
sgp130 (ng/ml)309.96 ± 42.31367.01 ± 81.54369.53 ± 61.03402.03 ± 53.26<0.001/<0.001
hsCRP (mg/l)0.47 ± 0.220.67 ± 0.501.20 ± 0.831.16 ± 0.74<0.001/NS
  • Data are means ± SD unless otherwise indicated. P values are derived from factorial ANOVA. All interactions between PCOS status and obesity are nonsignificant. Postload glucose and insulin refer to value at 120 min of the oral glucose tolerance test.