TABLE 1

Changes in body weight and blood glucose level with resveratrol treatment

Body weight (g)Blood glucose (mmol/l)
C-CC-RD-CD-RC-CC-RD-CD-R
Week 028.3 ± 0.327.7 ± 0.521.2 ± 0.520.4 ± 0.48.7 ± 0.19.0 ± 0.325.4 ± 0.827.5 ± 0.9
Week 227.6 ± 0.326.3 ± 0.421.1 ± 0.621.1 ± 0.59.0 ± 0.27.4 ± 0.231.8 ± 0.729.6 ± 0.8
Week 428.5 ± 0.327.8 ± 0.420.6 ± 0.621.2 ± 0.58.3 ± 0.27.9 ± 0.231.2 ± 0.827.7 ± 1.2*
  • Data are means ± SE (n = 10). Resveratrol (in 0.5% CMC) at a dose of 20 mg/kg of body weight and 0.5% CMC alone were administered daily to control and diabetic mice, respectively, by oral gavage for 4 weeks. Time points were 0, 2, and 4 weeks after administration of resveratrol and CMC to control and diabetic mice, respectively, 1 month after STZ treatment: C-C and C-R, CMC- and resveratrol-treated control mice, respectively; D-C and D-R, CMC- and resveratrol-treated diabetic mice, respectively.

  • *P < 0.05 compared with CMC- and resveratrol-treated diabetic groups.