TABLE 2

Adjusted hazard ratios (HRs; 95% CI) for incident heart failure (HF) according to A1C categories

Models*Categories of A1C, range (%)trend P
<5.05.0–5.45.5–5.96.0–6.4
Model 1
    No. of cases/subjects50/1,012307/5,263361/3,883123/899
    HR (95% CI)0.92 (0.68–1.24)Reference1.44 (1.24–1.68)2.04 (1.63–2.54)<0.001
Model 2
    No. of cases/subjects45/970289/5,078338/3,707111/840
    HR (95% CI)0.96 (0.70–1.31)Reference1.16 (0.98–1.36)1.38 (1.09–1.75)0.006
Model 3
    No. of cases/subjects45/955285/5,002329/3,642110/824
    HR (95% CI)0.96 (0.70–1.32)Reference1.16 (0.98–1.37)1.40 (1.09–1.79)0.008
  • *Model 1: adjusted for age, race, and sex. Model 2: model 1 + level of education, carotid atherosclerosis, systolic blood pressure, antihypertensive medication, smoking, alcohol intake, BMI, LDL-C, HDL-C, a history of CHD at baseline, and eGFR. Model 3: model 2 + fasting glucose.

  • †Participants with all variables used in model 2.

  • ‡Participants with all variables used in model 2 and fasting glucose.