TABLE 4

Adjusted* HRs (95% CI) for incident HF according to the combination of A1C and fasting glucose categories

Categories of fasting glucose, mmol/lCategories of A1C, %
<5.05.0–5.45.5–5.96.0–6.4
<5.0
    No. of cases/subjects10/15129/57622/2125/26
    HR (95% CI)1.99 (1.04–3.81)1.42 (0.94–2.15)1.75 (1.10–2.79)3.57 (1.45–8.79)
5.0–5.5
    No. of cases/subjects15/444104/2,15183/1,07525/131
    HR (95% CI)0.83 (0.49–1.44)Reference1.18 (0.88–1.58)2.19 (1.40–3.43)
5.6–6.0
    No. of cases/subjects17/288108/1,736126/1,49932/312
    HR (95% CI)1.15 (0.68–1.92)1.11 (0.85–1.45)1.16 (0.89–1.51)1.29 (0.86–1.94)
6.1–6.9
    No. of cases/subjects3/8748/615107/92149/371
    HR (95% CI)0.62 (0.20–1.96)1.20 (0.85–1.70)1.44 (1.09–1.90)1.38 (0.97–1.96)
  • *Adjusted for age, race, and sex, level of education, carotid atherosclerosis, systolic blood pressure, antihypertensive medication, smoking, alcohol intake, BMI, LDL-C, HDL-C, a history of CHD at baseline, and eGFR.